Position
Director, Pediatric Respiratory Medicine, Montreal Children’s Hospital
Professor, Department of Pediatrics, McGill University
Associate Member, McGill School of Dietetics & Human Nutrition, McGill University
Research Theme
Inhaled RNA and small molecule therapeutics, modulation of innate immunity, exercise limitation, pulmonary physiology.
Keywords
Cystic fibrosis (CF), primary ciliary dyskinesia (PCD), severe asthma, lipid nanoparticles, mucus rheology, immune modulation, exercise, oscillometry, translational research
Research Interests
Our translational research lab is focused on developing therapeutics in Cystic Fibrosis, Primary Ciliary Dyskinesia, severe asthma, and COPD. We are developing inhaled RNA and small molecule therapeutics using lipid nanoparticles. We are also working to understand how to prevent lung inflammation caused by Interleukin-17. Other work examines how we can rejuvenate basal cells to repair damaged lung epithelium. We utilize primary respiratory epithelial cells from nasal and airway brushings and lung biopsies and have established a Primary Ciliary Dyskinesia epithelial cell bank. Clinical research is oriented to understanding exercise limitation in chronic lung diseases, obesity, and cancer. We are also developing a non-invasive technique called oscillometry to detect early lung disease in Cystic Fibrosis and infants living with chronic lung disease.
Larry Lands in the News

New funding for a research project focusing on CF rare genetic mutations
Génome Quebec and Cystic Fibrosis Canada funding for project to develop genetic therapy for CV patients with rare mutations.

King Charles III Coronation Medal Awarded to RESP Members
Jean Bourbeau and Larry Lands receive the King Charles III Coronation Medal for their outstanding contributions to Lung Health.

Trikafta Prolongs the Lives of Cystic Fibrosis Patients
Larry Lands and Elias Matouk take part in a Radia-Canada digital feature about Trikafta, a drug for Cystic Fibrosis

Spring 2023 Student Awards
Congratulations to the 2023 recipients of FRQS and CIHR studentship and fellowship awards! We wish you much success!

RESP Research Day Oral and Poster Presenter Winners – 2023
Congratulations to all of our oral and poster presenter winners from the 2023 Respiratory Research Day.

MUHC Trottier Webster Innovation Award Goes to RESP Team
Congrats to Ben Smith, Jun Ding and Larry Lands! The team received the MUHC Trottier Webster Innovation Award for their work to repair damaged lungs in COPD.

Health Matters: Reprogramming Lungs Against COPD
MUHC Foundation Health Matters interview with Ben Smith discusses reprogramming COPD lungs and with Deborah Assayag discusses ILD

Meakins and RESP Trainees Receive QRHN Funding 2021-2022
Congratulations to Wided Akik and Lisa Hennemann for their 2021-2022 QRHN awards

Spring 2021 Student Awards
Congratulations to the recipients of FRQS and CIHR studentship and fellowship awards! We wish you much success!
Contact Information
Meakins-Christie Laboratories
RI-MUHC, Block E
Office EM3.2220
Lab E03.2155
1001 Decarie Blvd.
Montreal QC H4A 3J1
Canada
Tel: 514-934-1934 Ext. 23803 (lab)
Tel: 514-934-1934 Ext. xxxxx (office)
Tel: 514-934-1934 Ext. 76172 (admin)
Fax: 514-933-3962
E-Mail: larry.lands [at] mcgill.ca
Education & Training
BSc (Math) McGill (1977)
MD, McGill (1981)
PhD (Med Sci) McMaster (1993)