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RESP Journal Club

2021-2022 RESP Journal Club
Welcome to the joint RESP JOURNAL CLUB with RECRU and Meakins members. This journal club is open to all clinical and research faculty, trainees, fellows, and residents. The goal of this journal club is to critically evaluate a research article (or topic) from both clinical and fundamental science perspectives. Publications will be jointly chosen by RECRU and Meakins faculty members, who will facilitate discussion of the article. The publications will cover the various research themes of the RESP program, with a focus on translational research. Presentations will be delivered by faculty and/or trainees/fellows and all discussions will be moderated. Articles will be distributed 1 week in advance of the Journal Club date.
Frequency: Monthly on Fridays at 12 noon via ZOOM

Friday September 24, 2021No meeting
Friday October 22, 2021John KimoffSabah HussainArticle 1: Reboxetine plus Oxybutynin for Obstructed Sleep Apnea Treatment A 1-week Randomized, Placebo-controlled, Double-Blind Crossover Trial
Article 2: Endogenous Excitatory Drive Modulating Respiratory Muscle Activity across Sleep–Wake States
Friday November 26, 2021Deborah AsssayagGregory FonsecaArticle 1: Family History of Pulmonary Fibrosis Predicts Worse Survival in Patients With Interstitial Lung Disease
Article 2: IL‐17A contributes to HSV1 infection‐induced acute lung injury in a mouse model of pulmonary fibrosis
Friday, February 18, 2022Sushmita PamidiBasil PetrofArticle 1:  Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea
Article 2Daily Exposure to Mild Intermittent Hypoxia Reduces Blood Pressure in Male OSA Patients with Hypertension
Friday March 18, 2022Marta KaminskaArticle 1: Effects of Obstructive Sleep Apnea and Obesity on 30-Day Readmissions in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Mediation Analysis
Friday April 8, 2022Benjamin SmithSimon RousseauArticle 1: Association between very to moderate preterm birth, lung function deficits and COPD at age 53 years. Lancet Resp Med Feb 2022
Article 2: Human distal airways contain a multipotent secretory cell that can regenerate alveoli. Nature March 2022
Friday May 6, 2022Kevin SchwartzmanArticle 1: Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis
Friday June 10, 202231st Annual Respiratory Research Day

Checklist and questions for presenters to integrate into their presentation and to use for moderating the discussion:

What is the stated rationale/motivation for this study?Is this an important clinical/scientific problem?
What is the stated hypothesis (or objective)?Does the hypothesis (or objective) address the stated rationale)?
What are the stated methods used to test the hypothesis (achieve the objective)?Will the methods test the stated hypothesis?
What are the results?Are the results presented appropriately?
What is the authors’ interpretation of the results?Do you agree with their interpretation?
Are they making inferences that go beyond what the data show?
(If a clinical study) Do the findings apply to our patient population?
(If an interventional clinical study) Is the effect size clinically meaningful?
What are the stated limitations of the study?Do you agree with the stated limitations?
Are there other limitations?
Does this study provide the definitive answer the original problem?
Are other studies needed?

RECRU Seminars

RECRU seminars: Fridays at 1pm

October 2, 2020Sushmita Pamidi
October 23, 2020Benjamin Smith
November 6, 2020Deborah Assayag
December 18, 2020Tania Janaudis-Ferreira
January 29, 2021Grant Presentations
February 19, 2021Anne Gonzalez
March 26, 2021John Kimoff
April 30, 2021Marta Kaminska
May 28, 2021Faiz Ahmad Khan
June 18, 2021Kevin Schwartzman