Skip to content

RESP Journal Club

2023-2024 RESP Journal Club
Welcome to the joint RESP JOURNAL CLUB with RECRU and Meakins members. This journal club is open to all clinical and research faculty, trainees, fellows, and residents. The goal of this journal club is to critically evaluate a research article (or topic) from both clinical and fundamental science perspectives. Publications will be jointly chosen by RECRU and Meakins faculty members, who will facilitate discussion of the article. The publications will cover the various research themes of the RESP program, with a focus on translational research. Presentations will be delivered by faculty and/or trainees/fellows and all discussions will be moderated. Articles will be distributed 1 week in advance of the Journal Club date.
Frequency: Monthly on Fridays at 12 noon via ZOOM

2023-2024 RESP Journal Club

December 8, 2023Sushmita Pamidi / Diana Escobar Olaya
TBCArticle 1:  
Article 2: 
January 12, 2024John Kimoff / Romeo Alam—–Article 1:  Adaptive servo-ventilation for sleep-disordered breathing in patients with heart failure with reduced ejection fraction (ADVENT-HF): a multicentre, multinational, parallel-group, open-label, phase 3 randomised controlled trial. 
February 2, 2024Kevin Schwartzman /TBCArticle 1:  Treatment Strategy for Rifampin-Susceptible Tuberculosis
March 15, 2024Jonathan Campbell / Bader AlkharisiTBCArticle 1:  Effect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial
May 3, 2024
11 am-noon
Benjamin Mappin-Kasirer / Bryan RossTBCArticle 1:  
Article 2: 
June 7, 2024Benjamin Smith / Amanda MarinoTBCArticle 1:  
Article 2: 

Checklist and questions for presenters to integrate into their presentation and to use for moderating the discussion:

What is the stated rationale/motivation for this study?Is this an important clinical/scientific problem?
What is the stated hypothesis (or objective)?Does the hypothesis (or objective) address the stated rationale)?
What are the stated methods used to test the hypothesis (achieve the objective)?Will the methods test the stated hypothesis?
What are the results?Are the results presented appropriately?
What is the authors’ interpretation of the results?Do you agree with their interpretation?
Are they making inferences that go beyond what the data show?
(If a clinical study) Do the findings apply to our patient population?
(If an interventional clinical study) Is the effect size clinically meaningful?
What are the stated limitations of the study?Do you agree with the stated limitations?
Are there other limitations?
Does this study provide the definitive answer the original problem?
Are other studies needed?

2023-2024 RECRU Seminars

RECRU seminars: Fridays at 1pm

October 13, 2023Benjamin SmithUnderstanding the intersection of inflammation and lung function trajectories across diverse populations to maximize lifelong health
October 20, 2023Deborah AssayagCIHR Lung Health Team grant – a personalized approach to autoimmune related ILD
November 24, 2023Jean Bourbeau & Sushmita PamidiClinical trial unit and training at the RI-MUHC: ACT/CANTRAIN
December 15Faiz Ahmad Khan
February 9, 2024Nicole EzerCIHR project: Eosnionphilia and post operative readmission after lung cancer resection
March 22, 2024Tania Janaudis-FerreiraEmerging results from an RCT of virtual rehabilitation for individuals with Long COVID
April 12, 2024Kevin Schwartzman
April 26, 2024Jonathon Campbell
June 21, 2024Bryan Ross

2022-2023 RESP Journal Club

October 21, 2022Deborah AssayagJun DingArticle 1:   The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality
Article 2:  An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
November 18, 2022Benjamin SmithJun DingArticle1: Engineering lipid nanoparticles for enhanced intracellular delivery of mRNA through inhalation
Article 2:  Exhaustion of airway basal progenitor cells in early and established chronic obstructive pulmonary disease
January 13, 2023Faiz Ahmed KhanPOSTPONED
February 3, 2023Sushmita PamidiBasil PetrofArticle 1: Inflammasome Activation: A Keystone of Proinflammatory Response in Obstructive Sleep Apnea
Article 2: Positive Airway Pressure Adherence, Mortality and Cardiovascular Events in Patients with Sleep Apnea
March 10, 2023Kevin Schwartzman Simon RousseauArticle 1: Tuberculosis Diagnoses Following Wildfire Smoke Exposure in California
Article 2: Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
May 12, 2023No Journal Club
June 2, 2023Marta KaminskaArticle 1: OSA Was Associated With the Human Gut Microbiota Composition and Functional Potential in the Population-Based Swedish CardioPulmonary bioImage Study

2022-2023 RECRU Seminars

September 9, 2022Benjamin Smith
October 14, 2022Bryan Ross
December 2, 2022Tania Janaudis-Ferreira
December 9, 2022Kevin Schwartzman
January 27, 2023Marc Parsons
February 3, 2023Jean Bourbeau
April 14, 2023Amanda Scanga, Teresa Gomes, Malhar Shah (Kaminska)
May 5, 2023Deborah Assayag
May 12, 2023Suurya Krishnan
May 26, 2023 2:00 PMNicole Ezer
June 9, 2023Sushmita Pamidi

2021-2022 RESP Journal Club

October 22, 2021John KimoffSabah HussainArticle 1: Reboxetine plus Oxybutynin for Obstructed Sleep Apnea Treatment A 1-week Randomized, Placebo-controlled, Double-Blind Crossover Trial
Article 2: Endogenous Excitatory Drive Modulating Respiratory Muscle Activity across Sleep–Wake States
November 26, 2021Deborah AssayagGregory FonsecaArticle 1: Family History of Pulmonary Fibrosis Predicts Worse Survival in Patients With Interstitial Lung Disease
Article 2: IL‐17A contributes to HSV1 infection‐induced acute lung injury in a mouse model of pulmonary fibrosis
February 18, 2022Sushmita PamidiBasil PetrofArticle 1: Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea
Article 2: Daily Exposure to Mild Intermittent Hypoxia Reduces Blood Pressure in Male OSA Patients with Hypertension
March 18, 2022Marta KaminskaArticle 1: Effects of Obstructive Sleep Apnea and Obesity on 30-Day Readmissions in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Mediation Analysis
April 8, 2022Benjamin SmithSimon RousseauArticle 1: Association between very to moderate preterm birth, lung function deficits and COPD at age 53 years. Lancet Resp Med Feb 2022
Article 2: Human distal airways contain a multipotent secretory cell that can regenerate alveoli. Nature March 2022
May 6, 2022Kevin SchwartzmanArticle 1: Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis

2021-2022 RECRU Seminars

September 3, 2021Deborah Assayag
October 8, 2021Benjamin Smith
October 15, 2021RECRU Meeting
November 5, 2021Khan (Chen)
December 3, 2021Marta Kaminska (Gomes)
December 10, 2021RECRU/TM Seminar: Brian Allwood
February 4, 2022Benjamin Smith
February 11, 2022Sushmita Pamidi
March 11, 2022Bryan Ross
April 22, 2022John Kimoff
June 9, 2022Sushmita Pamidi

2020-2021 Journal Club

November 20, 2020John KimoffCarolyn BagloleArticle 1: Factors associated with COVID-19-related death using OpenSAFELY
Article 2: Cigarette Smoke Exposure and Inflammatory Signaling Increase the Expression of the SARS-CoV2 Receptor ACE2 in the Respiratory Tract
December 11, 2020Sana SwalehDao NguyenArticle 1: Intravenous versus oral antibiotics for eradication of Pseudomonas aeruginosa in cystic fibrosis (TORPEDO-CF): a randomised controlled trial
Article 2: Pseudomonas aeruginosa Strain-sharing in Early Infection Among Children WithCystic Fibrosis
January 29, 2021Faiz Ahmad KhanArticle 1: Chest x-ray analysis with deep learning-based software as a triage test for pulmonary tuberculosis: a prospective study of diagnostic accuracy for culture-confirmed disease
February 12, 2021Kevin SchwartzmanMaziar DivangahiArticle 1: Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis
Article 2: Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination
March 19, 2021Deborah AssayagGregory FonsecaArticle 1: Telomere Length and Genetic Variant Associations with Interstitial Lung Disease Progression and Survival
Article 2: Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
April 16, 2021Marta KaminskaArticle 1: The Sleep Apnea-specific Pulse Rate Response Predicts Cardiovascular Morbidity and Mortality
May 14, 2021Nicole EzerJames MartinArticle 1: Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial
Article 2: The Inhaled Steroid Ciclesonide Blocks SARS-CoV-2 RNA Replication by Targeting the Viral Replication-Transcription Complex in Cultured Cells
June 11, 2021Bryan RossDennis JensenArticle 1: Submaximal Eccentric Cycling in People With COPD Acute Whole-Body Cardiopulmonary and Muscle Metabolic Responses
Article 2: Are the “critical” inspiratory constraints actually decisive to limit exercise tolerance in COPD?

2020-2021 RECRU Seminars

June 4, 2021Bryan Ross
June 18, 2021Marta Kaminska