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RESP Journal Club

2022-2023 RESP Journal Club
Welcome to the joint RESP JOURNAL CLUB with RECRU and Meakins members. This journal club is open to all clinical and research faculty, trainees, fellows, and residents. The goal of this journal club is to critically evaluate a research article (or topic) from both clinical and fundamental science perspectives. Publications will be jointly chosen by RECRU and Meakins faculty members, who will facilitate discussion of the article. The publications will cover the various research themes of the RESP program, with a focus on translational research. Presentations will be delivered by faculty and/or trainees/fellows and all discussions will be moderated. Articles will be distributed 1 week in advance of the Journal Club date.
Frequency: Monthly on Fridays at 12 noon via ZOOM

October 21, 2022Deborah Assayag, MDJun Ding, PhDArticle 1:   The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality
Article 2:  An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
November 18, 2022Benjamin Smith, MDJun Ding, PhDArticle1: Engineering lipid nanoparticles for enhanced intracellular delivery of mRNA through inhalation
Article 2:  Exhaustion of airway basal progenitor cells in early and established chronic obstructive pulmonary disease
January 13, 2022Faiz Ahmed Khan, MD
February 3, 2023Sushmita Pamidi, MD
March 10, 2023Kevin Schwartzman, MD
May 12, 2023Bryan Ross, MD
June 2, 2023Marta Kaminska, MD

Checklist and questions for presenters to integrate into their presentation and to use for moderating the discussion:

What is the stated rationale/motivation for this study?Is this an important clinical/scientific problem?
What is the stated hypothesis (or objective)?Does the hypothesis (or objective) address the stated rationale)?
What are the stated methods used to test the hypothesis (achieve the objective)?Will the methods test the stated hypothesis?
What are the results?Are the results presented appropriately?
What is the authors’ interpretation of the results?Do you agree with their interpretation?
Are they making inferences that go beyond what the data show?
(If a clinical study) Do the findings apply to our patient population?
(If an interventional clinical study) Is the effect size clinically meaningful?
What are the stated limitations of the study?Do you agree with the stated limitations?
Are there other limitations?
Does this study provide the definitive answer the original problem?
Are other studies needed?

RECRU Seminars

RECRU seminars: Fridays at 1pm